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7 min read 2022-03-23 18:00:02

Switching neurons on and off to probe autism circuits

Much of modern biology is built on addition and subtraction. To interrogate a gene’s function, subtract it from the genome and watch what happens

5 min read 2022-03-15 23:31:23

To think that what we are witnessing now in Ukraine is far removed from the world of autism would be a huge mistake. I was fortunate to travel to

3 min read 2022-01-21 19:00:00

Listen to this story: One paper is about the aesthetic beauty of plant landscapes. Another reviews the use of anesthetic drugs in cancer patients.

3 min read 2022-01-07 19:00:00

Listen to this story: Researchers have uncovered thousands of new alternate RNA versions, or isoforms, of brain-expressed genes, including some

4 min read 2021-12-02 07:00:00

Autism prevalence in the United States rose to 1 in 44 children in 2018, up from 1 in 54 in 2016, according to a new study examining autism

1 min read 2021-10-26 18:00:00

Activating serotonin receptors in the medial septum, a region along the brain’s midline, reverses social-memory deficits in a mouse model of

1 min read 2021-10-19 18:00:00

The gut microbiome is having a moment. An explosion of research over the past decade has delved into a possible connection between the microbiome and

1 min read 2021-10-19 07:00:00

Common and rare variants in or near certain autism-associated genes can have opposite effects on cognition. Likewise, some autistic people carry

2 min read 2021-04-01 18:00:00

Listen to this story: A new atlas profiles gene activity early in development in the human fetal brain. The resource could help researchers

3 min read 2021-02-05 19:00:00

A new engineered protein that glows in the presence of serotonin enables researchers to track the neurotransmitter’s levels and location in the

3 min read 2020-12-21 19:00:00

A drug that has been tested in clinical trials as a treatment for depression restores social memory in a mouse model of 22q11.2 deletion syndrome,

3 min read 2020-12-17 19:00:00

People with autism who carry DNA variants in the same protein-coding region of a gene have more similar cognitive abilities and behaviors than those

5 min read 2020-12-07 19:00:00

In 1983, psychologist Christopher Gillberg posed a provocative question to the readers of the British Journal of Psychiatry: Could autism and

4 min read 2020-11-25 12:00:05

Spectrum is covering the 2020 International SYNGAP1 Scientific Conference, which took place virtually because of the coronavirus pandemic. Here

3 min read 2020-11-05 19:00:00

A small clinical trial of a gene therapy for Angelman syndrome — a rare genetic condition related to autism — is on hold after two participants